
Metformin
Gold-standard biguanide for blood sugar, longevity, and anti-aging research.
Why Metformin.
Blood glucose reduction via AMPK
Longevity and anti-aging research support
Cardiovascular risk reduction
Cancer risk reduction signals in literature
About Metformin.
Metformin is one of the most prescribed medications globally, primarily for type 2 diabetes management. Beyond glycemic control, extensive research supports its role as a longevity compound — activating AMPK, reducing mTOR signaling, and being associated with reduced all-cause mortality in observational studies.
How it works.
From intake to your first dose — four straightforward steps.
Complete intake
A brief health questionnaire reviewed by our clinical team. Takes about 5 minutes.
Provider review
A board-certified clinician reviews your history within 48 hours.
Compounded & shipped
Your prescription is compounded in a licensed US pharmacy and shipped to your door.
Ongoing support
Telehealth follow-up to adjust your protocol as needed.
Ready to start Metformin?
Complete a brief health intake and a licensed provider will review your request within 48 hours. No commitments.
All prescriptions are issued at the sole discretion of licensed providers. Protocol Health Rx does not guarantee prescription approval.